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Two major research articles on Jewish DNA appeared in June. As reported by Nicolas Wade in the New York Times in an article titled "Studies Show Jews' Genetic Similarity," they settle an old controversy. One of the surveys of genomic or autosomal DNA was conducted by Gil Atzmon of the Albert Einstein College of Medicine and Harry Ostrer of New York University and appears in the American Journal of Human Genetics. The other, led by Doron M. Behar of the Rambam Health Care Campus in Haifa and Richard Villems of the University of Tartu in Estonia, is published in the journal Nature. The two teams reached similar conclusions independently and simultaneously. Their findings refute the long-standing contention that Jews “have no common origin but are a miscellany of people in Europe and Central Asia who converted to Judaism at various times.”

One of the articles, published online June 9, and in print July 8, was "The Genome-Wide Structure of the Jewish People," (Nature 466, 238-42). The editors' summary for it goes like this:

A comparison of genomic data from 14 Jewish communities across the world with data from 69 non-Jewish populations reveals a close relationship between most of today's Jews and non-Jewish populations from the Levant. This fits in with the idea that most contemporary Jews are descended from ancient Hebrew and Israelite residents of the Levant. By contrast, the Ethiopian and Indian Jewish communities cluster with neighbouring non-Jewish populations in Ethiopia and western India, respectively. This may be partly because a greater degree of genetic, religious and cultural crossover took place when the Jewish communities in these areas became established.

An abstract for the other article mentioned by the New York Times, "Abraham's Children in the Genome Era," is given as follows by the publisher, The American Journal of Human Genetics:

For more than a century, Jews and non-Jews alike have tried to define the relatedness of contemporary Jewish people. Previous genetic studies of blood group and serum markers suggested that Jewish groups had Middle Eastern origin with greater genetic similarity between paired Jewish populations. However, these and successor studies of monoallelic Y chromosomal and mitochondrial genetic markers did not resolve the issues of within and between-group Jewish genetic identity. Here, genome-wide analysis of seven Jewish groups (Iranian, Iraqi, Syrian, Italian, Turkish, Greek, and Ashkenazi) and comparison with non-Jewish groups demonstrated distinctive Jewish population clusters, each with shared Middle Eastern ancestry, proximity to contemporary Middle Eastern populations, and variable degrees of European and North African admixture. Two major groups were identified by principal component, phylogenetic, and identity by descent (IBD) analysis: Middle Eastern Jews and European/Syrian Jews. The IBD segment sharing and the proximity of European Jews to each other and to southern European populations suggested similar origins for European Jewry and refuted large-scale genetic contributions of Central and Eastern European and Slavic populations to the formation of Ashkenazi Jewry. Rapid decay of IBD in Ashkenazi Jewish genomes was consistent with a severe bottleneck followed by large expansion, such as occurred with the so-called demographic miracle of population expansion from 50,000 people at the beginning of the 15^th century to 5,000,000 people at the beginning of the 19^th century. Thus, this study demonstrates that European/Syrian and Middle Eastern Jews represent a series of geographical isolates or clusters woven together by shared IBD genetic threads.

Critics of the new research findings point out that there are still no known markers for Jewish ancestry in genomic DNA. They obviously are not among our customers, however, since those who have purchased the 18 Marker Ethnic Panel available since last year are routinely screened for Jewish I, Jewish II and Jewish III. Their locations on genomic DNA were discovered by the company last August. 

A Jewish genetic signature expressed in terms of autosomal DNA was predicted last year in a study titled, "A Genome-Wide Genetic Signature of Jewish Ancestry Perfectly Separates Individuals with and without Full Jewish Ancestry in a Large Random Sample of European Americans," by Ann C. Need et al. (Genome Biology 2009, vol. 10). That study spoke of "near perfect genetic inference of Ashkenazi Jewish ancestry." Interestingly, it also foresaw that "the genetic distinction between Jews and non-Jews may be more attributable to a Near-Eastern [i.e. Middle Eastern] origin for Jewish populations than to population bottlenecks." [American usage favors "Middle East" over the British and outdated "Near East" still retained in academia.]

A final study of Jewish autosomal DNA that deserves mentioning is "Genomic Microsatellites Identify Shared Jewish Ancestry Intermediate between Middle Eastern and European Populations," published also last year in BMC Genetics, vol. 10, by Naama M. Kopelman et al. It used 678 autosomal microsatellite loci in 78 individuals, but what is proven on a large scale seems equally true on the small scale of our three Jewish markers based on microsatellites forming part of your DNA fingerprint.